What Is Lupus? Know The Causes, 10 Symptoms And Best Treatments!

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Published on: 19-Apr-2024

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What Is Lupus? Know The Causes, 10 Symptoms And Best Treatments!

What Is Lupus? Know The Causes, 10 Symptoms And Best Treatments!

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Lupus was once much more life-threatening than it is today. Now, most people with lupus can live 10 years or more beyond their early diagnosis. But what is lupus? Lupus, medically known as systemic lupus erythematosus (SLE), is a chronic autoimmune disease affecting various body parts, including the skin, joints, kidneys, heart, lungs, and brain. In lupus, the immune system mistakenly attacks healthy tissues and organs, leading to inflammation and damage. 

While the exact cause of lupus is not fully understood, a combination of genetic, environmental, and hormonal factors is believed to contribute to its development. Women of childbearing age are at a higher risk of developing lupus, although it can affect people of all ages, genders, and ethnicities. Lupus symptoms vary widely and may come and go over time, making diagnosing challenging. Common symptoms include fatigue, joint pain, skin rashes, fever, and sensitivity to sunlight. 

According to recent Lupus Foundation reports, Lupus is not fatal in most cases, and 80–90% of patients can expect to live an extended life span with treatments and follow-up care. However, in some severe cases, lupus causes organ damage and life-threatening complications. Early detection and treatment are crucial for managing symptoms and preventing disease progression. Thus, this blog explores the best lupus treatments available to manage its symptoms effectively. So, keep reading! 

Table Of Contents 

1. What Is Lupus Disease? And Is Lupus A Serious Disease? 

2. What Is The Main Cause Of Lupus? And Is Lupus Life Threatening? 

3. 10 Lupus Symptoms You Need To Recognise  

4. Major Lupus Symptoms: Know Early Signs Of Lupus In Females 

5. Is Lupus Treatable? Best Lupus Treatment Options  

6. Dietitian’s Recommendation 

7. The Final Say 

8. FAQs 

9. References 

What Is Lupus? And Is Lupus A Serious Disease? 

Lupus is a chronic (long-term) disease that can cause inflammation and pain anywhere in the body. Lupus occurs when the immune system attacks its tissues, which helps protect the body from infection and disease. Inflammation caused by lupus can affect various systems in the body, including joints, skin, kidneys, blood cells, brain, heart, and lungs.   

Because the signs and symptoms of lupus are often like those of other diseases, it can be challenging to diagnose. However, some people are born predisposed to developing lupus, which can be caused by infections, certain medications, or even sunlight exposure. The most characteristic sign of lupus is a facial rash that resembles the spread of butterfly wings on both cheeks, which occurs in many, but not all, cases of lupus.   

There is no cure for lupus, but treatment may help control symptoms. If you have lupus, you may experience periods of illness (outbreaks) and better health (remission). Lupus outbreaks can range from mild to severe and are unpredictable. However, with treatment, many people with lupus can overcome the disease.   

Systemic lupus erythematosus (SLE) is the most common type of lupus, meaning it is all over your body, but there are other types. Other types include:   

  • Cutaneous lupus erythematosus - Lupus that affects only the skin.   

  • Drug-induced lupus - Some medications cause lupus symptoms as a side effect. This is usually temporary and may go away when you stop taking the medication  

  • Neonatal lupus - Sometimes, children are born with lupus. A child born to a biological parent with lupus does not necessarily have lupus but may be at increased risk.  

What Is The Main Cause Of Lupus? And Is Lupus Life Threatening? 

The cause of lupus is unknown, but genetic factors may play a role. Even though researchers have not yet determined the exact trigger, one study suggests the following possible triggers:   

Cause of Lupus 

Effect 

Is it Life Threatening? 

Genetic factors 

Specific genetic mutations may increase the risk of developing lupus. These mutations can affect the immune system, making it more prone to attacking healthy cells and tissues. 

While genetic factors can predispose individuals to lupus, the condition is not typically life-threatening solely due to genetic mutations. 

Hormones 

The body's response to certain hormones, particularly estrogen, may increase lupus risk. Hormonal fluctuations can influence the immune system, potentially triggering lupus flares. 

Although hormones can influence lupus development, the condition is generally not considered life-threatening solely due to hormonal factors. 

Environmental factors 

Location, pollution, and sunlight exposure can affect the risk of developing lupus. Exposure to pollutants and UV radiation can trigger inflammation and immune responses in susceptible individuals. 

Environmental factors can contribute to lupus development but don't typically pose an immediate life-threatening risk alone. 

Health history 

Smoking and high stress levels can exacerbate inflammation while existing autoimmune conditions can increase the risk of developing lupus. 

Factors like smoking, stress, and other medical conditions can exacerbate lupus symptoms, potentially increasing the risk of complications and thus posing a life-threatening risk. 

Sunlight 

Sun exposure can cause lupus skin lesions or trigger internal reactions in sensitive individuals. UV radiation can activate immune cells and lead to inflammation, contributing to lupus symptoms. 

While sunlight exposure can worsen lupus symptoms, severe reactions are rare, making it typically non-life threatening. 

Infection 

Infections can cause lupus or trigger flare-ups in some individuals. Infections can stimulate the immune system, potentially leading to autoimmune responses and worsening lupus symptoms. 

Infections can exacerbate lupus symptoms, potentially leading to life-threatening complications, especially in severe cases. 

Medications 

Certain medications like blood pressure meds, anticonvulsants, and antibiotics can cause drug-induced lupus. Symptoms may improve upon stopping medication but, in rare cases, may persist. 

Drug-induced lupus can lead to severe complications, though symptoms often resolve after discontinuing the medication, making it typically reversible and non-life-threatening. 

10 Lupus Symptoms You Need To Recognise


Lupus causes symptoms throughout the body, depending on which organ or system is affected. Everyone has a different combination of symptoms and severity. Lupus symptoms usually come and go in waves called flares. During a relapse, symptoms may be severe enough to affect daily life. There may be periods of remission when symptoms are mild or absent. Symptoms usually appear slowly. You may notice one or two signs of lupus first and more symptoms later. 

The most common yet alarming lupus symptoms include:   

1. Pain Throughout The Body 

Lupus can cause widespread pain, known as lupus arthralgia or myalgia. This pain can affect the joints, muscles, and even organs, leading to discomfort and reduced mobility for many patients. The severity of pain can vary from mild to debilitating, and it may come and go in flare-ups. Managing pain is an essential aspect of lupus treatment, often requiring a combination of medications, physical therapy, and lifestyle modifications. 

2. Butterfly-Shaped Rash 

One of the hallmark symptoms of lupus is a butterfly-shaped rash across the cheeks and nose, often called a malar rash. This rash can vary in severity and appearance, ranging from mild redness to raised and scaly patches. It typically worsens with sun exposure and may come and go with lupus flares. While not all lupus patients develop this rash, its presence can aid in diagnosis and prompt treatment initiation. 

3. Intermittent Fever And Fatigue 

Many lupus patients experience intermittent fever and persistent fatigue as symptoms. Fever can be a sign of inflammation or infection, both common in lupus. Fatigue, on the other hand, can be debilitating and may significantly impact daily functioning, also causing chronic fatigue syndrome. Managing these symptoms often involves addressing underlying inflammation, immune system dysfunction, and lifestyle modifications to conserve energy. 

4. Swollen Sweat Glands 

Swollen sweat glands, or lymphadenopathy, can occur in lupus patients, particularly during flares or increased disease activity. This swelling results from the immune system's response to inflammation and can occur in various body parts, including the neck, underarms, and groin. Treatment typically focuses on managing the underlying inflammation and may involve medications to suppress the immune system. 

5. Worsen Skin Lesions 

Lupus can cause a variety of skin lesions, including discoid lupus lesions, which are characterised by raised, scaly patches on the skin. These lesions can worsen during lupus flares or with sun exposure, leading to increased discomfort and potential scarring. Treatment often involves topical or oral medications to reduce inflammation and promote healing, along with sun protection measures to minimise further damage. 

6. Shortness Of Breath 

Shortness of breath, or dyspnea, can occur in lupus patients due to inflammation of the lungs or involvement of the heart and blood vessels. This symptom can range from mild to severe and may be accompanied by chest pain, coughing, or wheezing. Prompt medical evaluation is essential to determine the underlying cause of shortness of breath and initiate appropriate treatment, which may include medications and lifestyle modifications. 

7. Sudden Memory Loss 

Lupus can affect the central nervous system, leading to cognitive dysfunction and memory problems in some patients. Sudden memory loss or difficulty concentrating can be alarming symptoms that warrant medical attention. These cognitive symptoms may fluctuate over time and can significantly impact daily functioning. Treatment may involve medications to manage inflammation and cognitive therapy to improve memory and cognitive function. 

8. Dry Eye Syndrome 

Dry eye syndrome is a common complication of lupus, resulting from inflammation of the tear glands or damage to the eye's surface. This can cause discomfort, redness, and blurred vision. Managing dry eye syndrome often involves lubricating eye drops, medications to reduce inflammation, and lifestyle modifications such as avoiding dry environments and using humidifiers. 

9. Common Mental Problems 

Lupus can have a significant impact on mental health, leading to symptoms such as depression, anxiety, and mood swings. Dealing with the challenges of chronic illness, along with the physical symptoms of lupus, can contribute to mental health issues for many patients. Treatment may involve therapy, support groups, and medications to address underlying mental health conditions. 

10. Sudden Convulsions Or Attacks 

Seizures or sudden convulsions can occur in some lupus patients, particularly those with central nervous system involvement. These episodes can be frightening and may require immediate medical attention. Treatment typically involves medications to control seizures, along with addressing underlying inflammation and immune system dysfunction. Close monitoring and adjustment of medications may be necessary to manage seizures effectively. 

Major Lupus Symptoms: Know Early Signs Of Lupus In Females  

Lupus is a chronic autoimmune disease that affects more women than men. Anyone can get lupus, but women are most at risk. Between the ages of 20 and 30, lupus is 15 times more likely to affect women than men. This difference is smaller in children (three times more often) and older adults (eight times more often), but still exists. Lupus most commonly occurs in women between the ages of 15 and 45 or when they are likely to have children. 

After lupus, your risk of other health problems increases. If you have lupus, you are at higher risk for other health problems that commonly occur in women, such as heart disease and osteoporosis. Lupus can be difficult to diagnose because it has a wide range of symptoms that can mimic other diseases. Early signs in women include fatigue, hair loss, joint pain, and swelling. However, diagnosis can be difficult because symptoms may be similar to other disorders. Thus, early diagnosis is essential to prevent complications. 

Is Lupus Treatable? Best Lupus Treatment Options  

Your doctor may suggest lupus treatments to help manage your symptoms. The goal is to minimise organ damage and the impact of lupus on your daily life. Most people with lupus need a combination of medications to prevent flare-ups and reduce the severity of symptoms. You may need:   

Lupus Treatment 

Impact 

Key Notes 

Hydroxychloroquine 

Hydroxychloroquine is a disease-modifying antirheumatic drug (DMARD) that relieves lupus symptoms and slows its progression. It helps to reduce inflammation and minimise organ damage associated with lupus. 

Hydroxychloroquine is often prescribed as a long-term treatment for lupus, but regular eye check-ups are necessary to monitor for possible side effects. 

Nonsteroidal anti-inflammatory drugs (NSAIDs) 

Over-the-counter NSAIDs relieve pain and reduce inflammation in lupus patients. Your doctor will recommend a specific type and dosage of NSAID based on your needs and medical history. 

Prolonged use of NSAIDs should be monitored closely by a healthcare professional to minimise the risk of gastrointestinal and cardiovascular side effects. 

Corticosteroids 

Corticosteroids are prescription medications that effectively reduce inflammation in lupus patients. Prednisolone is a commonly prescribed corticosteroid administered orally or through injections directly into affected joints. 

Long-term use of corticosteroids may lead to osteoporosis, weight gain, and increased susceptibility to infections. Regular monitoring is essential for bone health. 

Immunosuppressants 

Immunosuppressants suppress the immune system's activity, helping to prevent tissue damage and inflammation in lupus patients. 

Due to their potential to weaken the immune system, patients on immunosuppressants should be closely monitored by their healthcare provider for infections and other adverse effects. 

Additional Treatments 

Some lupus patients may require additional medications or treatments to manage specific symptoms or complications caused by the disease. This may include treatments for anaemia, high blood pressure, or osteoporosis. 

Lupus treatment plans are individualised based on each patient's unique symptoms, medical history, and overall health status. 

Dietitian’s Recommendation 

Lupus is generally not a fatal disease. Its effects can be controlled through lifestyle changes, a healthy diet, regular exercise, and prescribed medications. The first step is to recognise lupus symptoms and see your doctor as soon as possible to avoid the fatal stages. 

Dt. Lavina Chauhan 

The Final Say 

Lupus can be challenging in India, but understanding the symptoms, potential causes, and available treatments is the first step towards managing it effectively. Don’t forget to value yourself, as pain, inflammation, and irritation throughout the body can be debilitating. Also, remember nutrition’s significant role in chronic disease management. This blog serves as a springboard for further exploration and discussion with your doctor. Don't hesitate to ask questions, voice your concerns, and work collaboratively to create a personalised treatment plan. By staying informed, adopting healthy habits, and advocating for your well-being, you can empower yourself to manage lupus and take control of your health journey 

FAQs 

1. What is systemic lupus erythematosus? 

Systemic lupus erythematosus (SLE), commonly known as lupus, is an autoimmune disease where the body's immune system mistakenly attacks healthy tissues and organs. This can lead to inflammation and damage in various body parts, including the skin, joints, kidneys, heart, lungs, and brain. 

2. What organ does lupus affect first? 

Lupus does not affect a specific organ first, as it can vary from person to person. However, it commonly affects the skin and joints initially in many patients. Some individuals may experience symptoms related to other organs, such as the kidneys, heart, or lungs, early in the disease course. Lupus is known for its unpredictable nature, with symptoms often flaring and remitting over time. 

3. Is it safe to try lupus self-care for effective results? 

While self-care practices such as maintaining a healthy lifestyle, managing stress, getting regular exercise, and getting enough rest can help improve overall well-being and may complement medical treatment for lupus, individuals with lupus need to work closely with their healthcare team. Self-care practices should be discussed with a doctor to ensure they are safe and appropriate for everyone's medical condition. 

4. How to avoid lupus? 

Unfortunately, there is no known way to prevent lupus, as the exact cause of the disease remains unknown. However, lifestyle factors may influence the risk of developing lupus or exacerbating symptoms. These include avoiding excessive sun exposure, quitting smoking, maintaining a healthy diet, exercising regularly, managing stress, and avoiding exposure to harmful chemicals or pollutants. 

References 

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